Recently, I got rid of the business line to my house. The downside to this is losing ports 25 and 80. Port 80 isn’t a real deal breaker as when I’m coding/debugging I’m just using a local webserver. However, when I am testing email functionality in an application things get a little more interesting. The fix I found for this involves how you specify the SMTP actions in the webconfig.
In your Configuration section, you can specify either network delivery or a pickup location: